A 2025: lateral flow test - our provisional answer
Two DP-tutors (Nico and Nyske) sat paper A this year as benchmarkers. When comparing our answers, it turned out that we had largely the same solution, differing only in details of the wording.We both stuck closely to the wording of the paper, and incorporated some embodiments of D1 into our (dependent) claims. D1 turned out (again) to have some useful things in it.
A claim 1 according to our solution could read something like:
1. Lateral flow test, comprising:
- a sample pad (1) for receiving a liquid sample (5),
- a conjugate pad (2), which is arranged downstream of the sample pad (1),
the conjugate pad (2) containing a detection agent (11),
the detection agent being a conjugate (11) of a first type antibody (10) and a coloured particle (9),
wherein the first type antibody (10) is adapted to specifically recognise and bind to a target
molecule (6) in the liquid sample and wherein the coloured particle has a spherical shape,
- a reaction membrane (3), which is arranged downstream of the conjugate pad (2),
which
reaction membrane (3) comprises a test line (7),
the test line (7) comprising second types antibodies (12) that are specific for the target molecule (6)
and are immobilised in a line across the surface of the membrane,
characterised in that the coloured particle is a spherical gold nanoparticle having a diameter
of 20 - 100 nm.